ABOUT  PIXIUM VISION

Vision: to create a world of bionic vision for those who have lost their sight.

Mission: To provide best in class bionic vision restoration systems enabling the blind to regain greater autonomy and improved quality of daily living.

With the implantation of Bionic Vision Restoration Systems (VRS) medical device, the blindness will be treated and the blind patient will be able to see again.

This system (VRS) is intended to replace the normal physiological functions of the eye’s photoreceptor cells by electrically stimulating the nerve cells of the inner retina, which then transmit the visual information to the brain via the optic nerve.
 

This Bionic VRS are built around three components:

An implantable part (the retinal implant) that contains electrodes.
A portable visual interface (goggles with a camera and a data transmission system) Huge black glasses.
A pocket processor (which is linked to the glasses)
 
TECHNOLOGY
Pixium Vision’s Bionic VRS are systems intended to replace the normal physiological functions of the eye’s photoreceptor cells by electrically stimulating the nerve cells of the inner retina, which then transmit the visual information to the brain via the optic nerve.
 
Due to its construction, the retina can be artificially stimulated in two ways:
Epi-retinal stimulation: The electrodes are placed on the surface of the retina, which involves sending a strong signal directly to the ganglion cells.
 
 
Sub-retinal stimulation: The electrodes replace the photoreceptor layer. That stimulates bipolar cells and the inner retina, which enables a more physiological processing of the visual signal.
 
 
PATIENTS - OVERVIEW
 
Innovative Bionic Vision Restoration technologies of Pixium Vision:
Pixium Vision’s Bionic VRS are systems intended to replicate the physiological functions of  the eye’s photoreceptors by electrically stimulating the retinal cells, which then transmit the visual information to the brain via the optic nerve.

The technologies currently focus on the disorders resulting from degeneration of photoreceptors.

Structure of the retina:
The retina is composed of several layers of cells that line the back of the eye. The layer photoreceptor cells converts light stimuli into electrical signals.

These signals are then sent to the cells forming the inner retina, where they undergo spatial and temporal processing before being transmitted to the ganglion cells located on the surface of the retina and whose axons form the optic nerve.

Lastly, the optic nerve transports the final signal to the visual cortex deep in the brain.

 

Photoreceptor degeneration:
Most degeneration diseases of the retina (whether of genetic origin or age-related) result  from the progressive or acute degeneration of photoreceptor cells; the retina can no longer convert light stimuli into electrical signals.

This degeneration of photoreceptors leaves the other retina cells, whether ganglion cells or the inner retina, remain functional. When these inner retinal cells are electrically stimulated, a visual stimulus can still be transmitted to the brain.

 

CLINICAL TRIAL

Compensation for blindness with the Intelligent Retinal Implant System (IRIS V2) in patients with Retinal Dystrophy (IRIS 2)
The IRIS system currently in clinical trial has been designed so that RP patients can perceive objects by recognizing their size, position, orientation and movement. Thus offering more autonomy and a better quality of life.

The objective of this advanced (VRS) is to enable patients to identify and pick up a cup, shake hands and recognize certain objects such as a plate, a table, a door or a chair in black and white.

 

 

For more information, kindly visit www.pixium-vision.com